PATH 501 Integrated Anatomy, Pathology, and Embryology

The first course in a two-course sequence consisting of a systems based approach to the study of human anatomy utilizing cadaver dissection, correlating gross and microscopic anatomy with associated pathologies and embryology. Includes lecture and laboratory.

Credits

6

Prerequisite

Matriculated Pathologists' Assistant Student

Offered

Spring

Outcomes

1. 1) Describe the gross anatomy of major human organ systems, including the nervous, cardiovascular, respiratory, musculoskeletal, and digestive systems, with an emphasis on their functional roles.
2. 2) Explain the relationship between anatomical structures and their physiological functions, emphasizing how anatomical changes can lead to dysfunction or disease.
3. 3) Define key pathological concepts including inflammation, neoplasia, degeneration, and metabolic disorders, and understand how they relate to anatomical structures.
4. 4) Analyze the relationship between anatomical abnormalities and disease manifestations, identifying how structural changes contribute to pathological processes.
5. 5) Describe the cellular and molecular mechanisms of disease such as apoptosis, necrosis, and fibrosis, and understand how these processes affect organ function.
6. 6) Examine the pathology of common congenital disorders, correlating anatomical defects with embryological disruption and genetic factors.
7. 7) List the stages of human embryonic development from fertilization to organogenesis, and identify key milestones in development.
8. 8) Describe the fundamental processes of cell differentiation and morphogenesis during early human development.
9. 9) Recite the formation and function of the primary germ layers (ectoderm, mesoderm, and endoderm) and their role in organ development.
10. 10) Integrate anatomical, pathological, and embryological perspectives to understand complex disease processes, such as congenital malformations, cancer, and degenerative diseases.
11. 11) Discuss the causes and effects of developmental disorders, including genetic and environmental factors, and their impact on embryonic development and anatomical structures.
12. 12) Identify common congenital anomalies, correlating them with disruptions in normal embryological development and their pathological consequences.
13. 13) Examine the role of teratogens and other environmental factors in the development of birth defects and understand how these factors disrupt normal developmental processes.
14. 14) Analyze the clinical significance of early prenatal screening in detecting developmental abnormalities, and understand how this integrates with anatomical and pathological findings.
15. 15) Identify the key molecular signaling pathways (e.g., Wnt, Notch, Hedgehog) involved in embryonic development and their relevance to pathologies.