PATH 555 Clinical Immunology and Microbiology

An exploration of the immune system and microbial world, emphasizing the interplay between host defense mechanisms and pathogens. Topics include elements of the immune system, signaling pathways, pathogen recognition, the immune system and cancer, as well as microbial pathogenesis, virology, parasitology, mycology,, and emerging infectious diseases.

Credits

3

Offered

Fall

Outcomes

1. 1) Compare and contrast the differences and shared characteristics of the innate and adaptive immune systems.
2. 2) Name the main cells of the immune system and identify where the cells originate.
3. 3) Define primary and secondary lymphoid organs.
4. 4) Define the functions of the phagocytic cells.
5. 5) Describe the activation events of the adaptive immune system.
6. 6) Describe the three functions of the complement system.
7. 7) Name 4 mechanisms of complement system regulation.
8. 8) Define complement deficiencies and how they relate to clinical disease.
9. 9) Define the role of memory B cells and memory T cells.
10. 10) Describe different mechanisms of vaccine development.
11. 11) Contrast the systemic immune system with the intestinal immune system.
12. 12) Describe the control systems and cell-type classification in cancer.
13. 13) Describe the role of cytotoxic T-lymphocytes in the body's ability to fight cancer.
14. 14) Describe the route of pathogenesis in common bacteria, viruses, and parasites.
15. 15) Compare and contrast gram negative and gram positive bacterial cells.